A pair of long-estranged twins — Milo (Bill Hader) and Maggie (Kristen Wiig) — are reunited through just-missed tragedy in Craig Johnson's indie dramedy. Maggie is contemplating suicide when she gets the call that Milo has been hospitalized in Los Angeles following his attempt. She invites him back to their small New York hometown to stay with her and her husband (Owen Wilson). There, the two siblings — once close, now variously emotionally messed up — fumble toward reconciliation and a lasting support system. The subject matter is serious, though the film is leavened by one epically bad '80s song and Milo and Maggie's acerbic wit. (That is, the viewer is amused while each siblings suffers the other's well-aimed barbs.) It's a film about personal growth, so don't expect a lot of plot. Do look for two great performances from Hader and Wiig, who dial back their comic chops to hit the bittersweet dramatic notes their sad, fake-happy, damaged and repressed characters demand.